In an article in the Canadian Medical Association Journal, David Bailey, a scientist at the Lawson Health Research Institute in London, Ontario, said more than 85 drugs, many of them highly prescribed for common medical conditions, are known to interact with the pink fruit.
He first made the link 20 years ago.
But the number of medications with the potential to interact with grapefruit and cause serious adverse health effects has jumped from 17 to 43 in the last four years, as new drugs have been rolled out, Bailey said.
"How big a problem are such interactions? Unless health care professionals are aware of the possibility that the adverse event they are seeing might have an origin in the recent addition of grapefruit to the patient's diet, it is very unlikely that they will investigate it," Bailey said.
Generally patients don't say they eat grapefruit and doctors don't ask, he lamented in the article.
Grapefruit poses a risk when mixed with certain drugs because it inhibits an enzyme that metabolizes ingested drugs, resulting in the drugs entering the bloodstream at full force, which can lead to overdosing.
Some of the drugs known to interact with grapefruit include anti-cancer agents, heart drugs, pain medications and drugs to treat schizophrenia. All of them are administered orally.
It doesn't take much grapefruit to have an effect. Drinking a single glass of grapefruit juice with medication can lead to serious side effects, including gastrointestinal bleeding, kidney failure, breathing problems and sudden death.
Other citrus fruits such as Seville oranges and limes can have similar effects. But they have been studied less.
Source: AFP Relaxnews | 30 November, 2012 13:45 | Times Live http://www.timeslive.co.za/lifestyle/2012/11/30/dangers-of-mixing-grapefruit-with-drugs-rises
The content of this website is provided for general informational purposes only and is not intended as, nor should it be considered a substitute for, professional medical advice. Do not use the information on this website for diagnosing or treating any medical or health condition. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider.
Dr JPB Prinsloo is the oldest Homoeopathic Practice in South Africa.
The Practice was established in 1956.
To learn more about homeopathic treatment visit: