Wednesday, 20 February 2013

Nicotine can boost blood vessel growth

Nicotine may not be all bad: A study found it stimulated new blood vessel growth in mice by actively signaling their bone marrow to release vessel-forming adult stem cells.

The finding might translate to the use someday of nicotine as a means of helping wound healing and other conditions where new blood vessel growth is key, experts say. It also gives insight into unwanted vessel growth, such as that which happens during tumor formation.

The findings, based on animal and test-tube research, are reported in the Dec. 19 issue of the Journal of the American College of Cardiology.

Cooke's team's prior research had already demonstrated nicotine's ability to promote blood vessel growth, known as the "angiogenic effect." In this new study, they set out to uncover the mechanism driving this process.

The findings don't mean doctors will ever recommend smoking, however.

Comment: That is because they remain ignorant of the following among others:
Nicotine - The Zombie Antidote
Let's All Light Up!
Pestilence, the Great Plague and the Tobacco Cure
Comets, plagues, tobacco and the origin of life on earth

Comment: Nicotine is not bad, on the contrary. Nicotine is related to acetylcholine - a neurotransmitter responsible for learning and memory. It is also calming, relaxing and is also a major factor regulating the immune system. Acetylcholine also acts as a major brake on inflammation in the body and inflammation is linked to every known disease. In classical studies, nicotine, isolated from tobacco, was one of the chemicals used to distinguish receptors for acetylcholine. That is why there are nicotinic receptors for acetylcholine.Nicotine has been used as an anti-inflammatory and to prevent kidney failure and improve kidney function. Nicotinic receptors in the brain are associated with neuronal plasticity and cell survival, which is why tobacco has been linked with better thinking and concentration.

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